Synonyms of sedativenext
: tending to calm, moderate, or tranquilize nervousness or excitement

sedative

2 of 2

noun

: a sedative agent or drug

Examples of sedative in a Sentence

Adjective some people find a glass of wine to be a civilized and sedative addition to an evening meal Noun The patient was given a powerful sedative.
Recent Examples on the Web
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Adjective
While one form, or isomer, of thalidomide has a sedative effect, the other is thought to cause abnormal physiological development. — Sajish Mathew, The Conversation, 7 Oct. 2026 As the lethal dose of the sedative pentobarbital began flowing, Ramey took a deep breath, sputtered and began snoring. — Michael Graczyk, Arkansas Online, 24 Sep. 2026
Noun
In 1961, however, studies in animals revealed that clozapine acts primarily as a sedative and exerts its effects without inducing muscle rigidity, as previous antipsychotics had. — Encyclopedia Britannica, 7 Oct. 2026 Pike, 50, who was sentenced to death for a 1995 murder, was administered two doses of just one drug, pentobarbital, a sedative. — Meg Tirrell, CNN Money, 2 Oct. 2026 See All Example Sentences for sedative

Word History

Etymology

Adjective

Middle English, alleviating pain, from Middle French sedatif, from Medieval Latin sedativus, from Latin sedatus

First Known Use

Adjective

1779, in the meaning defined above

Noun

1797, in the meaning defined above

Time Traveler
The first known use of sedative was in 1779

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Cite this Entry

“Sedative.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sedative. Accessed 14 Oct. 2026.

Kids Definition

sedative

1 of 2 adjective
: tending to calm or to ease tension

sedative

2 of 2 noun
: a sedative medicine

Medical Definition

sedative

1 of 2 adjective
: tending to calm, moderate, or tranquilize nervousness or excitement
sedative effects of anesthetics and analgesics—Linda C. Haynes et al.

sedative

2 of 2 noun
: a sedative agent or drug

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